Best UFC 321 Bets: Main Event, Major Matches, Undercard

Written By:

Michael Molter

Published On:

October 24, 2025 3:54 PM

Best UFC 321 Bets: Main Event, Major Matches, Undercard
  • Jose Delgado has -145 odds to win against Nathaniel Wood in the earlier bouts of the day.
  • On the first UFC undercard event, Aleksandr Rakic and Azamat Murzakanov have a pick em matchup.
  • Tom Aspinall is a massive favorite over Cyril Gane in the main event, as the heavyweight titleholder fights again.

ABU DHABI – In the main event of UFC 321, Tom Aspinall takes on Ciryl Gane as a heavy favorite. The heavyweight titleholder hasn’t fought in a year and a half but has won his last three bouts by KO/TKO.

A hard hitter, 12 of his last 14 fights have ended in the first round, evident by UFC betting sites favoring him to win in Round 1, 2 or 3 (-200 odds).

As for Cyril Gane, he hasn’t had the best results in his last five, at 3-2. Fighting only once in the last two years, Gane often wins by decision or (late) TKOs.

Though UFC sportsbooks have Aspinall as a -390 favorite, bettors can cheapen these odds by selecting a prop bet on Bovada instead.

  • Tom Aspinall to Win & Round 2 to Start -120

Aleksandr Rakic vs Azamat Murzakanov

In a battle of some light heavyweights near the middle of the UFC rankings, #7 Aleksandr Rakic takes on #10 Azamat Murzakanov in a pick em.

Rakic is 0-3 in his last three fights (losing two by TKO) and has fought twice since 2024. As for Murzakanov, he’s 5-0 in the UFC (15-0 overall), with four TKO/KOs on the UFC stage.

With two performances of the night, Murzakanov could be the favorite here, but he isn’t. A tough UFC bout to bet on, it might be easier to add this leg to your parlay: The fight to complete 1 Full Round at -385 odds.

Nathaniel Wood vs Jose Delgado

In one of the earlier fights of the night, Nathaniel Wood takes on Jose Delgado at 11:45 a.m. ET.

For Wood, the last eight of his bouts went to decision (6-2 record) while his first few came with quicker endings. As for Delgado, he’s only 2-0 in the UFC but has made his case known. Winning two bouts in Round 1 by ground strikes, Delgado comes in with a great advantage.

  • Wood: 5’6”, 69” reach
  • Delgado: 5’11”, 73″ reach

With Delgado having fought in London this year in March, we’re taking Jose Delgado to win by KO, TKO or DQ at +185 odds.

Those looking for a safer legal sports betting play might arbitrage two decisions: A KO/TKO/DQ finish at +125 odds and a Decision finish at +110.

This way, as long as a submission victory doesn’t occur, bettors will return a 10-25% return.

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Ben Fiore

Michael Molter

Michael Molter has worked with LegalSportsBetting since 2018 starting as a content writer. Now the Director of Content, his work analyzes how laws, licensing, and compliance directly impact bettors and operators across jurisdictions. His research has been cited by NASDAQ, Research Gate, and PokerNews, as well as in academic reports from Villanova, Seton Hall, and Fairleigh Dickinson University.