Clemson - Wake Forrest Matchup

  • The Clemson Tigers are 7.5 favorites against Wake Forest and the Tigers have not lost to the Demon Deacons since the 2008 season.
  • Clemson had a record ATS during the 2021 season of 4-8 and have gone 1-2during the 2022 season and Wake is their first ACC and top 25 matchup.

WINSTON-SALEM, NC. – The Clemson Tigers are taking on the Wake Forest Demon Deacons and are 7.5 favorites to win the game on the road. Clemson has historically dominated their ACC rival and has not lost to Wake since the 2008 season.


  • Clemson -285
  • Wake Forest +235

The Tigers have a 7.5 spread to cover but have not been efficient this season ATS, gong 1-2. The Demon Deacons are Clemson’s first top 25 and ACC opponent for the 2022 season and their recent struggles point towards betting on them to not cover against Wake.

During the 2021 regular season, Clemson went 4-8 ATS and failed to cover the spread in two of their four games played as the favorite on the road.

Betting on a QB Advantage for Wake

Even though Wake Forest has not been able to defeat the Tigers in the last decade, Clemson does not have the QB advantage for their 2022 matchup. Sam Hartman was not able to start the season for Wake due to injury, but returned in week 2 and has thrown 625 yards, seven TDs and only two interceptions in 2022.

In three games for Clemson, D.J. Uiagalelei has thrown a total of 662 yards, five TDs and one interception. Hartman started 14 games in 2021, while Uiagalelei started 13 and statistically had a much less efficient season.

2021 QB Stats

Player Pass Yards Rush Yards Total TDs Interceptions
Sam Hartman 4,228 363 50 14
D.J. Uiagalelei 2,246 308 13 10

Betting on Game Props

Along with the 54.0 total that has -110 odds to hit the over/under, sites with legal betting have props for the exact winning margin and alternative spreads. As the underdog, Wake Forest has long odds to win by 1-6 points or more.

  • Clemson By 1-6 +330
  • Clemson By 7-12 +400
  • Clemson By 13-18 +500
  • Wake Forest By 1-6 +475
  • Wake Forest By 7-12 points +525
  • Wake Forest By 13-18 +1800

There are also odds for the first scoring methods of the game. During the teams last two matchups, the first score has been by Clemson, with a FG in 2021 and TD in 2020.  Betting on Clemson scoring first for the third time could pay out big at legal sites with college football betting.

  • First Score Method
  • Field Goal +275
  • TD -400
  • Other +4000
  • First Team to Score
  • Clemson -160
  • Wake Forest +120
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