Pick The Padres As Underdogs In Game 1 vs The Giants

Written By:

Drew Gniadek

Published On:

August 11, 2025 12:09 PM

Giants Given Upper Hand In 7th Meeting With Padres Monday
  • The San Francisco Giants have -142 odds to defeat the San Diego Padres at home in a divisional matchup.
  • San Diego has won their last four consecutive series entering Monday’s game.

SAN FRANCISCO – An NL West showdown begins Monday night as the San Francisco Giants host the San Diego Padres for the first game of their third series this season. San Diego leads the season series 4-2 overall through six games.

Padres vs Giants Game Odds

Team Spread Moneyline Total
Padres +1.5 (-180) +119 O 7.5 (EVEN)
Giants -1.5 (+155) -142 U 7.5 (-120)

The Giants are favored at home on legal sports betting sites, which give San Francisco -142 odds to win outright. With a low implicated run total and -180 odds for the Padres to cover the one and a half run spread, here are some key stats to consider for what should be a tightly contested game.

Pitching Matchup

Pitching is a strength for both of these teams, each ranking inside the top five in ERA as a team in the MLB.

However, the pitching matchup falls in favor of the Giants, who will start lefty Logan Webb against Yu Darvish for San Diego.

Webb has gone 10-8 in 24 starts with a 3.24 ERA this season and is fifth in the MLB with 165 strikeouts. He’s struck out just 29 less batters in just under 60 less innings than his career best 2023 season where he struck out 194 batters in 216 innings pitched.

Yu Darvish has missed most of the season to this point, making just six starts, which have resulted in a 1-4 record with a 6.51 ERA. Darvish has been named an All-Star five times during his 13 year career, most recently in 2021, but it is evident that his best days are behind him.

Home vs Road Splits

The Giants have been largely unimpressive at home this season, going just 29-28, the 20th best home record in the MLB. Their 3.63 runs per game at home plays a major role in their mediocre home record, the second least runs per game at home in the league.

Fortunately for San Francisco, the Padres have not been any better on the road, going 28-32 away from home and scoring 3.93 runs per game on the road, the fifth worst mark in the MLB.

Recent Performance

The Padres have been drastically better than the Giants since the All-Star break, going 14-8 for the fourth best record in that span. They’ve won four straight series since splitting 2-2 with the St. Louis Cardinals and beat a Boston Red Sox team who has been on fire as of late.

The Giants, on the other hand, have been one of the worst teams in baseball since the break, going 7-14, just half a game out of the worst record in the league during that span.

Since acquiring Rafael Devers in June, the Giants have had the fourth worst record in the league at 18-28 and have averaged the fewest runs per game during that time with just 3.89 runs per game.

Despite having Webb on the mound, the offensive struggles for San Francisco are still a massive concern and facing a Padres team playing some of their best baseball, it is surprising that the Giants are favored in this one.

Bet on the Padres to win this game outright before the oddsmakers can adjust at MLB betting sites.

Advertising Disclosure

In order to provide you with the best independent sports betting news and content LegalSportsBetting.com may receive a commission from partners when you make a purchase through a link on our site.

Ben Fiore

Drew Gniadek

Drew is currently a student at Florida State University, originally from Massachusetts. He has a background playing basketball, including both for the high school varsity team and pool basketball with his friends. Drew is a die-hard Celtics fan and also enjoys football and baseball.