- Bryant Wesco Jr. is poised to build on his strong true freshman season and is a great bet to go over his receiving yards prop against LSU.
- Garrett Nussmeier is a good bet to throw for over 289.5 passing yards versus Clemson because he averaged more than 311 yards passing per game last season, and LSU may have to throw the ball a lot based on game script.
- Because of their elite defensive line and explosive offense, Clemson is a good bet to cover the spread in Week 1 at home versus LSU.
CLEMSON, S.C. – Bryant Wesco Jr. over receiving yards, Garrett Nussmeier over 289.5 passing yards, and the Clemson Tigers covering the spread as 3.5-point favorites over the LSU Tigers are the three best bets for the showdown between the top ten teams in Week 1.
Clemson vs LSU Odds
| Equipo | Spread | Moneyline | Total |
|---|---|---|---|
| LSU | +3.5 (-110) | +150 | O 57.5 (-110) |
| Clemson | -3.5 (-110) | -175 | U 57.5 (-110) |
- Note: There are no college football player props offered at locally regulated betting sites in Louisiana, and there are no state-sponsored betting sites in South Carolina. Due to those limitations, legal offshore sportsbooks such as BetOnline and Bovada are the best option for people trying to find where and how to bet on LSU vs Clemson in South Carolina or Louisiana.
Bet on Bryant Wesco Jr. Receiving Yards vs LSU
Last season, star true freshman wide receivers were a key storyline. Jeremiah Smith and Ryan Williams were the headliners, so much so that they are on the cover of College Football 26.
Due to those two superstars, Bryant Wesco Jr. somewhat fell under the radar. Some notable stats from his true freshman season include:
- Wesco Jr. averaged 59 yards per game over the full season.
- Over the final five games of the year, he was even better. He averaged 75.2 yards per game over that stretch, with 61+ yards in four of the five games.
Based on his season-long average and his strong close to the season, Bryant Wesco Jr.’s receiving yards prop is simply too low.
The best college football betting sites with player props for Wesco Jr. are Bovada and BetOnline. Wesco Jr.’s receiving yard lines are slightly different at the sportsbooks:
- Bryant Wesco Jr. Receiving Yards Prop at Bovada: Over 56.5 Yards: -110/Under 56.5 Yards: -110
- Bryant Wesco Jr. Receiving Yards Prop at BetOnline: Over 55.5 Yards: -113/Under 56.5 Yards: -115
Based on those odds and betting lines, BetOnline is likely the best sportsbook for betting on Wesco Jr. because his receiving yards total is slightly lower than at Bovada.
Bet on Garrett Nussmeier Passing Yards vs Clemson
Garrett Nussmeier threw for 311.7 passing yards per game last season.
Despite that, legal sports betting sites have Nussmeier’s passing yards prop line set at 289.5 with -114 odds for the over.
That 20+ yard difference between his passing yards per game last season and his prop line is enough of a reason to bet the over.
Additionally, the people who bet on Nussmeier’s passing yards are also likely to benefit from the fact that LSU may be in passing situations throughout the game, as they are underdogs.
Bet on Clemson to Cover the Spread vs LSU
LSU is a very highly rated team and is likely ranked in the AP Poll as the ninth-best team going into the season for good reason, but there are two main reasons to like Clemson to defend their Death Valley and cover the 3.5-point spread as favorites:
- Clemson’s defensive line vs LSU’s offensive line: Clemson’s defensive line is headlined by Peter Woods and TJ Parker this season. Woods (1st) and Parker (9th) both ranked inside of Dane Brugler’s initial top 10 for the 2026 NFL Draft. LSU’s offensive line brought in some experienced transfers, notably Paul Mubenga and Braelin Moore, but they have just lost four offensive linemen to the draft (Will Campbell, Emery Jones Jr., Miles Frazier, and Garrett Dellinger), so they are likely to be inexperienced.
- Clemson’s offense vs LSU’s defense: Clemson, led by Cade Klubnik, Antonio Williams, and Wesco Jr., should be an outstanding unit this season. They return eight starters and face an LSU defense that only brings back three. Clemson should light up the LSU defense.
Given the strength of their defensive line and strong offense, bet on Clemson to cover the spread versus LSU to open the season.
- Writer’s Note: Clemson is 0-2 with a combined score of 62-10 in their past two season openers, which were against Georgia (34-3 in 2024) and Duke (28-7 in 2023). LSU has not won a season opener since Joe Burrow was the quarterback in their 2019 National Championship season. They have lost to USC (27-20 in 2024), Florida State (45-24 in 2023 and 24-23 in 2022), UCLA (38-27 in 2021), and Mississippi State (44-34) since then. If you are not comfortable betting on either team to win an opener, stick to Bryant Wesco Jr. and Garrett Nussmeier props.
