Arizona Wildcats

  • From the past 20 years, nine of the last 19 championships have been from the South Region.
  • The Arizona Wildcats have the second-best odds to win the title with +600.

TUCSON, Ariz. – The South Region has been given the longest odds to win the 2022 NCAA tournament despite the teams in the South Region heating up.

Arizona is on a six-game winning streak, Villanova has a five-game winning streak, and Tennessee has a seven-game winning streak. Also, these three teams all won their conference championship game.

Region Odds To Win The Tournament 2022

  • South Region +375
  • West Region +245
  • Midwest Region +175
  • East Region +245

Betting on the South Region at legal sportsbooks offers leniency with five legitimate teams that could win the tournament.

South Region Teams Odds

  • Arizona +600
  • Villanova +1500
  • Tennessee +1600
  • Houston +2800
  • Illinois +5000

The Villanova Wildcats won the NCAA tournament in 2018 and 2016 and are entering the 2022 tournament as a two seed. They have been one of the hotter teams in the South and have won nine of their last 10 games.

They have -1600 odds for their first-round matchup with Delaware on Thursday.

The Arizona Wildcats won the Pac 12 tournament by overcoming a 12-point lead by UCLA and are entering the NCAA tournament with a number one seed. Since 1987, 20 teams with a one seed have won the tournament.

Arizona had to wait to find out their first opponent, but are favored by 21.5 over the Wright State Raiders.

A team in the South Region has won the NCAA tournament nine times out of the last 19 tournaments or 47%.

Teams To Win From The South Region Since 2010

  • 2010: Duke
  • 2012: Kentucky
  • 2015: Duke
  • 2017: North Carolina
  • 2019: Virginia
  • 2021: Baylor

The only team with better odds to win the NCAA tournament than Arizona is the Gonzaga Bulldogs, with +300 odds.

To make matter worse, famous sports bettor Jim “Mattress Mack” McIngvale put down $1 million on the East Region to win the tournament.

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