WWE Wrestlepalooza Betting Odds + Predictions

Written By:

Sam Profeta

Published On:

September 17, 2025 6:03 PM

WWE Wrestlepalooza Betting Odds + Predictions
  • John Cena has -500 odds to beat Brock Lesnar.
  • CM Punk and AJ Lee are favored to beat Seth Rollins and Becky Lynch with -2000 odds.
  • Cody Rhodes is favored to beat Drew McIntyre with -2500 odds.
  • There are +350 odds for the Usos to beat Bronson Reed and Bron Breakker.

INDIANAPOLIS – The newest PLE to WWE’s roster, Wrestlepalooza, is set to take place on Saturday as a part of the first of many to stream on ESPN’s premium package.

With that said, from top to bottom, this is a loaded card with some massive matches taking place, leaving plenty of odds to check out on legal sports betting sites. The main event fight will continue John Cena’s farewell tour with his match against Brock Lesnar.

Cena Continues Winning On Farewell Tour With Lesnar

John Cena Vs. Brock Lesnar Odds

  • Cena -500
  • Lesnar +300

There should be no questions here about John Cena’s odds to win. A loss on this Farewell Tour would certainly put a damper on things, especially his historic rivalry with Brock Lesnar. Even in their memorable matches since Lesnar’s 2012 return, Cena has a 2-1 record over him.

That said, do not overthink this one, take Cena to win at whatever unit size, and enjoy what should be a great match.

AJ Lee Wins In First Match Since Return

CM Punk & AJ Lee Vs. Seth Rollins & AJ Lee Odds

  • Punk/Lee -2000
  • Rollins/Lynch +700

There is absolutely no way that in her first match since returning to WWE, AJ Lee is going to lose this match. Especially given the build up to this one through the rivalry between Punk and Rollins. Rollins and his vision have gotten the best of CM Punk in recent weeks, so a win here for Punk would make sense, especially with his wife by his side in her return.

Rhodes Successful In First Title Defense

Cody Rhodes Vs. Drew McIntyre Odds

  • Rhodes -2500
  • McIntyre +800

This marks Cody Rhodes’ first title defense since winning the title back from John Cena at SummerSlam. While Drew McIntyre is a worthy enough opponent for Rhodes this time around, it’s hard to see WWE moving on from Rhodes this quickly.

Uso’s Cash Plus Money Over Reed & Breakker

The Usos Vs. Bronson Reed & Bron Breakker Odds

  • Usos +350
  • Reed/Breakker -600

This is where things could get interesting for those looking for plus money at WWE betting sites. Both Jimmy and Jey Uso have been tossed around like ragdolls by Bronson Reed and Bron Breakker. Whether it’s a spear from Breakker or Tsunami from Reed, one of them has ended up being flattened on Monday Night Raw in recent weeks.

That said, we could see the Usos finish their story against Reed and Breakker here in this one with a win. However, that will not come without the help of their cousin, the Tribal Chief, Roman Reigns, who has also had his fair share of issues with Breakker and Reed. That said, expect Reigns to make an appearance in this one and push the Usos to a win.

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Ben Fiore

Sam Profeta

Samuel has been writing professionally for 4 years. He comes from a sports writing background where he enjoys writing mostly about basketball and football both professional and collegiate. He is a recent graduate of Florida State University where he majored in Editing, Writing and Media with a minor in Communications. During his free time, you can find him watching or playing sports as well as playing videogames and listening to music.