Novak Djokovic and Serena Williams

  • Novak Djokovic has the shortest odds at +150 to win the 2021 Men’s Australian Open.
  • Naomi Osaka’s +150 odds are the shortest to win the 2021 Women’s Singles Australian Open.
  • Grigor Dimitrov is a -225 moneyline favorite to defeat Aslan Karatsev who is listed at +185 odds.

LAS VEGASThe Australian Open has reached the quarterfinal stage with the final eight tennis players remaining in both the men’s and women’s divisions.

Now is one of the best times to place a wager on any tennis betting odds before the semifinal matchups are set.

On the men’s side of the Australian Open tennis legends in Novak Djokovic and Rafael Nadal are still alive in the tournament but will face stiff competition moving forward.

For Djokovic, he is looking to capture his ninth career Australian Open Championship. Djokovic and Nadal could meet in the Australian Open final for the third time. Both previous matches were won by Djokovic. However, for these two to meet in the final they’ll have to advance in the next two rounds.

Australian Open Men’s Quarterfinal Betting Odds

Grigor Dimitrov vs. Aslan Karatsev Odds

  • Moneyline: Dimitrov (-225) vs. Karatsev (+185)
  • Spread: Dimitrov (-4.5)
  • O/U: 38.5

The winner of this Dimitrov-Karatsev matchup will likely face Djokovic next should he beat Zverev in the quarterfinals. This will be the first time Dimitrov and Karatsev have faced off in their careers and Dimitrov is the more experienced tennis player having won eight titles to Karatsev zero.

The best bet for this matchup is to take Dimitrov to cover the –4.5-point spread.

Novak Djokovic vs. Alexander Zverev Odds

  • Moneyline: Djokovic (-190) vs. Zverev (+160)
  • Spread: Djokovic (-3.0)
  • O/U: 39.5

For Djokovic to make his third consecutive Australian Open Final he will need to have a strong showing against Alexander Zverev who has defeated the No. 1 overall tennis player twice in his career. Djokovic has bested Zverev five times including victories in their last four matchups.

Take the -190 moneyline odds on Djokovic to advance to the semifinals.

Andrey Rublev vs. Daniil Medvedev Odds

  • Moneyline: Rublev (+225) vs. Medvedev (-285)
  • Spread: Medvedev (-4)
  • O/U: 39.5

Rublev-Medvedev have faced each other three times in their careers with each time being in the quarterfinal round. Daniil Medvedev has beaten Rublev each of the three times they’ve faced each other, and bettors should expect this trend to continue. Take the -285 odds on Medvedev to advance to the semifinal round to face the winner of Tsitsipas-Nadal.

Rafael Nadal vs. Stefanos Tsitsipas Odds

  • Moneyline: Nadal (-220) vs. Tsitsipas (+180)
  • Spread: Nadal (-3.5)
  • O/U: 40.5

Nadal and Tsitsipas will face each other for the eighth time in their careers in the Australian Open quarterfinals. Nadal has dominated this matchup winning six of the seven meetings including the last three matchups against Tsitsipas. Take the -220 moneyline odds that Nadal wins as those odds are also perfect to add to any parlay.

If not wanting to bet on the game lines, Bovada has also listed futures odds for the 2021 Australian Open.

Odds To Win 2021 Men’s Australian Open

  • Novak Djokovic +150
  • Daniil Medvedev +275
  • Rafael Nadal +425
  • Alexander Zverev +700
  • Stefanos Tsitsipas +800
  • Andrey Rublev +1200
  • Grigor Dimitrov +1400
  • Aslan Karatsev +6600

Australian Open Woman’s Quarterfinals Betting Odds

On the women’s side, Serena Williams and Naomi Osaka remain alive in the Australian Open and they could meet in the semifinals if both win their quarterfinal matchups. The betting odds for those quarterfinal matches are:

Su-Wei Hsieh vs. Naomi Osaka Odds

  • Moneyline: Hseih (+575) vs. Osaka (-850)
  • Spread: Osaka (-6)
  • O/U: 19

Osaka is heavily favored and rightfully so as she remains one of the top active tennis players currently. Hseih is a very solid player and could make this closer than expected but bettors should lean towards taking Osaka ATS as the -850 moneyline odds should only be added to a parlay.

Serena Williams vs. Simona Halep Odds

  • Moneyline: Williams (-130) vs. Halep (+105)
  • Spread: Williams (-1.5)
  • O/U: 21.5

The path for Serena Williams to win her first Australian Open tournament since 2017 brings her a familiar opponent in Simona Halep. These two have faced each other 12 times previously with Serena holding the edge with a 9-3 record. However, Halep did win the last matchup between the two when Halep defeated Williams in the Wimbledon Finals. This will likely be the most anticipated matchup for those betting on the Australian Open Quarterfinals and the moneyline odds for either player is a viable option.

Ashleigh Barty vs. Karolina Muchova Odds

  • Moneyline: Barty (-475) vs. Muchova (+350)
  • Spread: Barty (-5)
  • O/U: 20.5

Ashleigh Barty and Karolina Muchova have only faced each other once in their careers. In their only meeting, Barty beat Muchova in two sets at the 2018 US Open. In the 2021 Australian Open, Barty is expected to defeat Muchova once again. If betting on Barty, look to bet ATS and if betting Muchova to pull off the upset the +350 money line odds present the best value.

Jennifer Brady vs. Jessica Pegula Odds

  • Moneyline: Brady (-250) vs. Pegula (+200)
  • Spread: Brady (-4)
  • O/U: 20.5

Two of the young up-and-coming American tennis players faceoff as Jennifer Brady takes on Jessica Pegula. Despite Brady being the favorite in the quarterfinal match, Pegula has won the only time these two have played each other. Pegula could very well pull off the upset here and her +200 odds on the moneyline are well worth the risk.

Outside of the match lines, Naomi Osaka is still favored to win the 2021 Australian Open with +150 odds. Another great option would be to place a small wager on Serena Williams +500 odds especially if she can advance to the semifinal round and then upset Naomi Osaka.

Odds To Win 2021 Women’s Australian Open

  • Naomi Osaka +150
  • Ashleigh Barty +250
  • Serena Williams +500
  • Simona Halep +600
  • Jennifer Brady +850
  • Karolina Muchova +2000
  • Jessica Pegula +2200
  • Su-Wei Hsieh +5000

Legal sports betting sites will be updating these future odds after each day of the tournament. The closer the tournament is to concluding the shorter the odds will get, possibly making the quarterfinals the best time to bet on the Australian Open.

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